From the back of the box:
"Step into the nightmare that could only belong to Daria as she leads you on an outlandish quest to save Lawndale. Experience the thrilling adventure of high school according to Daria and try all of the computer game stuff like puzzles, quests and mazes. Adventure? Well, maybe that's too strong a word. Voyage through the five circles of Daria's netherworld as she finds herself lost in a nightmare she can't escape. Only you can help her wake up by solving the mysteries of Ms. Li's missing stuff. Doom has never been so bleak. Meet all the characters from the Daria show and hear Daria's pithy, sharp-witted commentary as she struggles to save the school. All dialogue written and performed by the same extremely clever people who created the show."
Truth be told, it's less of a game & more of an interactive episode, so if you're a fan of the show, you'll likely love it. One small caveat - some of the speech is rather repetitive, & the game is rather short & easy, even without the hints disguised as "Sick, Sad World" promos.